ExVivo Organ and Tissue Preservation Studies
Our cardiovascular emulating CaVESWave ® laboratory platform is allowing clinicians and researchers to advance organ preservation through novel oxygen delivery technologies, perfusates, cellular, drug, and gene therapies evaluated ex vivo and in vivo in pre-clinical animal and human models.
Specialty Lab Services and BioMarker Assays
BioMedInnovations (BMI) offers access to advanced laboratory services to support biomarker discovery and analysis methods such as immune monitoring, genomics, and bioanalysis to accelerate drug, vaccine and therapeutic development.
Our full-service suite of services come with powerful translational informatics and computational biology approaches that maximize information from each sample and study subject. The goal is to allow predictive modeling and biomarker signature development in transplant immunology, organ preservation, and drug discovery.
Examples of services provided include:
Tissue analysis (histopathology, cellular and molecular imaging),
Cell profiling (flow cytometry and mass cytometry),
Biomarker analysis (multiplex cytokine assays),
Pharmacokinetic and pharmacodynamic testing (LC/MS-MS with advanced quadrupole instrumentation),
Genomic quantitation (nCounter Nanostring ® assay).
BMI services proactively address challenges of sample size and statistical methodology in translational sciences.
BMI offers expert biostatisticians and statistical programmers to craft detailed study plans, including precise definitions of endpoints and descriptions of analyses, to address regulatory risks and maximize success from the outset.
Our Team of Experts
Leading research and innovation expert in perfusion technology
Significant knowledge and network within the medical arena.
Led national and Federal award winning response to COVID-19 crisis
2020, US Secretary of Defense awarded the Defense Meritorious Service Medal to Dr. Gerber for exceptionally meritorious service for the Armed Forces.
In 2010 David was appointed by the Secretary of the Department of Health and Human Services (HHS) to the Advisory Committee on Transplantation.
Special Advisor on Capitol Hill
Government and key stakeholder relations specialist
Helped forge industry/academic partnerships and PPP’s
Mark helped forge BMI’s relationships with Dr. Prabir Roy-Chaudhury MD, Ph.D, FRCP, co-Director of the Kidney Center UNC Chapel Hill, and with Dr. Tony Atala, MD, founding Director of the Wake Forest Institute of Regenerative Medicine, and negotiated the establishment of a new Recove laboratory based at the WFIRM ReMDO RegeneratOR in Winston-Salem.
14 years from research and development of perfusion tech
Co-author of many peer reviewed publications and papers
Leading the BMI lab at Duke Hospital
30+ years of engineering experience from US security clearance systems
US veteran who has held security clearance
Worked on multiple groundbreaking medical advancement systems